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Anaemia
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Anaemia

Where cow colostrum is used for rearing, acute anaemia could occur due to antigens which attack or get attached to the red blood cells.
The lambs become pale, slow (inactive) and die if they are not treated in time. 

Treatment consists of a blood transfusion. The chance of anaemia as a result of feeding cow's colostrum can be prevented by asking a veterinary surgeon to check the colostrum for anaemia and/or by mixing the colostrum of several cows. It is safer though to use a colostrum substitute.